Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | APAF1 | O14727 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MPO | P05164 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | ECE1 | P42892 | 6/20 | 0.61 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.61 |
| ▸ | ITGAL | P20701 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263833 | 0.90 | KDM4E (0.72) | ACEKDM4EMAPTAPAF1POLB | |
| SCHEMBL19737124 | 0.90 | ACE (0.70) | ACEKDM4EMAPTAPAF1POLB | |
| SCHEMBL1263822 | 0.90 | KDM4E (0.72) | ACEKDM4EMAPTAPAF1POLB | |
| SCHEMBL16750046 | 0.90 | ACE (0.70) | ACEKDM4EMAPTAPAF1POLB | |
| SCHEMBL15592745 | 0.90 | ACE (0.70) | ACEKDM4EMAPTAPAF1POLB | |
| SCHEMBL10610833 | 0.89 | ACE (0.63) | ACEKDM4EMAPTAPAF1POLB | |
| SCHEMBL5870457 | 0.88 | ACE (0.68) | ACEKDM4EMAPTAPAF1POLB | |
| SCHEMBL8254531 | 0.88 | ACE (0.68) | ACEKDM4EMAPTAPAF1POLB | |
| SCHEMBL29114797 | 0.86 | ACE (0.65) | ACEKDM4EMAPTAPAF1POLB | |
| SCHEMBL7222741 | 0.86 | ALOX15 (0.66) | ACEKDM4EMAPTAPAF1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030195144-A1 | Antimicrobial compounds and formulations | LYTIX BIOPHARMA AS (NO) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195144-A1 | Antimicrobial compounds and formulations | LPO, CLPTM1, VIP | ACE 2786/4885KDM4E 4487/4885MAPT 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.