Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197671 | 0.85 | HSD11B1 (0.56) | HSD11B1ALDH1A1MAPK1NOTUMCYP3A4 | |
| SCHEMBL11967616 | 0.84 | HSD11B1 (0.49) | HSD11B1ALDH1A1MAPK1PIK3R1PIK3CA | |
| Hydrochloric Acid SCHEMBL29010139 | 0.83 | HSD11B1 (0.54) | HSD11B1ALDH1A1MAPK1NOTUMCYP3A4 | |
| SCHEMBL8022901 | 0.83 | HSD11B1 (0.54) | HSD11B1ALDH1A1MAPK1NOTUMCYP3A4 | |
| SCHEMBL3998099 | 0.82 | HSD11B1 (0.47) | HSD11B1ALDH1A1MAPK1PIK3R1PIK3CA | |
| SCHEMBL29447944 | 0.80 | CA1 (0.54) | HSD11B1ALDH1A1NOTUMCA1CA2 | |
| SCHEMBL363301 | 0.80 | CA1 (0.54) | HSD11B1ALDH1A1NOTUMCA1CA2 | |
| SCHEMBL14127381 | 0.80 | CA1 (0.54) | HSD11B1ALDH1A1NOTUMCA1CA2 | |
| SCHEMBL1453604 | 0.78 | CA1 (0.52) | HSD11B1ALDH1A1NOTUMCA1CA2 | |
| Water SCHEMBL11569092 | 0.78 | CA1 (0.52) | HSD11B1ALDH1A1NOTUMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104326952-A | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL CO | 2015-02-04 | — | — | CN | disclosed |
| CN-104277004-A | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL CO | 2015-01-14 | — | — | CN | disclosed |
| CN-103180300-A | Process for producing pyridazinone compound and intermediate thereof | SUMITOMO CHEMICAL CO | 2013-06-26 | — | — | CN | disclosed |
| US-7893306-B2 | Process for production of biphenyl derivatives | TORAY FINE CHEMICALS CO., LTD. (JP) | 2011-02-22 | — | — | US | disclosed |