Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 9/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.69 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.69 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.69 |
| ▸ | XDH | P47989 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.69 |
| ▸ | DAPK1 | P53355 | 4/20 | 0.69 |
| ▸ | BACE1 | P56817 | 4/20 | 0.69 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22738241 | 0.90 | MEN1 (0.78) | APPMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL12639989 | 0.86 | MEN1 (0.68) | APPMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL8816390 | 0.86 | APP (0.74) | APPMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL12639930 | 0.84 | APP (0.71) | APPMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL10716775 | 0.83 | MEN1 (0.79) | APPMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL28432225 | 0.83 | MEN1 (0.85) | APPMEN1KMT2ACYP1A2CYP1A1 | |
| Datiscetin SCHEMBL30822630 | 0.83 | APP (1.00) | APPMEN1KMT2ACYP1A2CYP1A1 | |
| Datiscetin SCHEMBL43916 | 0.83 | APP (1.00) | APPMEN1KMT2ACYP1A2CYP1A1 | |
| Datiscetin SCHEMBL29737517 | 0.83 | APP (1.00) | APPMEN1KMT2ACYP1A2CYP1A1 | |
| Myricetin SCHEMBL3503992 | 0.82 | MEN1 (1.00) | APPMEN1KMT2ACYP1A2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935714-B2 | Compositions for sleeping disorders | Bright Future Pharmaceutical Laboratories (HK) | 2011-05-03 | — | — | US | disclosed |
| US-7935714-B2 | Compositions for sleeping disorders | Bright Future Pharmaceutical Laboratories (HK) | 2011-05-03 | — | — | US | disclosed |
| US-20090124627-A1 | COMPOSITIONS FOR SLEEPING DISORDERS | CHAN HSIAO CHANG | 2009-05-14 | — | — | US | disclosed |
| US-20090124627-A1 | COMPOSITIONS FOR SLEEPING DISORDERS | CHAN HSIAO CHANG | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124627-A1 | COMPOSITIONS FOR SLEEPING DISORDERS | PER2, CRY1, CRY2 | APP 661/4885MEN1 4015/4885KMT2A 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.