Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12640002 | 0.86 | EPHX1 (0.47) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL16280888 | 0.85 | EPHX1 (0.51) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL13273957 | 0.83 | EPHX1 (0.49) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL16280887 | 0.83 | EPHX1 (0.58) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL16549327 | 0.82 | EPHX1 (0.56) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL18877598 | 0.82 | EPHX1 (0.56) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL12985150 | 0.81 | EPHX1 (0.56) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL12984684 | 0.77 | EPHX1 (0.61) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL12984679 | 0.76 | NOD1 (0.51) | EPHX1SIRT6SIRT1 | |
| SCHEMBL11529874 | 0.76 | POLB (0.51) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314106-B2 | Substituted diketopiperazine analogs for use as drug delivery agents | MANNKIND CORPORATION (US) | 2012-11-20 | — | — | US | disclosed |
| US-20110158935-A1 | Substituted Diketopiperazine Analogs for Use as Drug Delivery Agents | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110158935-A1 | Substituted Diketopiperazine Analogs for Use as Drug Delivery Agents | DNPEP, NPEPPS, DHPS | EPHX1 4330/4885ALDH1A1 3745/4885POLB 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.