Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | USP5 | P45974 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18825263 | 0.81 | RAB9A (0.66) | RAB9ASMN1; SMN2TSHRALDH1A1MEN1 | |
| SCHEMBL18825265 | 0.81 | SMN1; SMN2 (0.66) | RAB9ASMN1; SMN2TSHRALDH1A1MEN1 | |
| SCHEMBL18825267 | 0.78 | SMN1; SMN2 (0.81) | RAB9ASMN1; SMN2TSHRALDH1A1MEN1 | |
| SCHEMBL18825272 | 0.77 | NPC1 (0.64) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL5846697 | 0.75 | SMN1; SMN2 (0.77) | RAB9ASMN1; SMN2TSHRALDH1A1KMT2A | |
| SCHEMBL13006683 | 0.74 | USP5 (0.50) | RAB9ASMN1; SMN2USP5ALDH1A1MEN1 | |
| SCHEMBL18825258 | 0.73 | SMN1; SMN2 (0.63) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14924022 | 0.73 | MEN1 (0.69) | SMN1; SMN2USP5ALDH1A1MEN1KMT2A | |
| SCHEMBL18825274 | 0.73 | RAB9A (0.59) | RAB9ASMN1; SMN2POLB | |
| SCHEMBL26744028 | 0.73 | RAB9A (0.59) | RAB9ASMN1; SMN2TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935782-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2011-05-03 | — | — | US | disclosed |
| US-20090306335-A1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | NATIONAL SCIENCE FOUNDATION | 2009-12-10 | — | — | US | disclosed |