Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 2/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 2/20 | 0.49 |
| ▸ | F3 | P13726 | 2/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21373212 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL21235517 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL21373214 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL21373211 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL21235418 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL21373213 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL21373209 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL20756762 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL21235636 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDFAAHMAPTCNR1 | |
| SCHEMBL21373207 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDFAAHMAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512449-B1 | METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | UNIV BRITISH COLUMBIA (CA) | 2019-08-07 | — | — | EP | disclosed |
| US-20160317676-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2016-11-03 | — | — | US | disclosed |
| US-20160317676-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2016-11-03 | — | — | US | disclosed |
| US-20130017223-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-01-17 | — | — | US | disclosed |
| US-20130017223-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-01-17 | — | — | US | disclosed |
| WO-2011075656-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130017223-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | LIPA, APOB, LIPC | ALDH1A1 4338/4885HPGD 4248/4885FAAH 1523/4885 |
| US-20160317676-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | LIPA, APOB, LIPC | ALDH1A1 4338/4885HPGD 4248/4885FAAH 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.