SCHEMBL1264057

SCHEMBL1264057

[CH2]C(OCCl)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
HTR2A P28223 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
SCN1A P35498 3/20 0.34
SCN2A Q99250 3/20 0.34
SCN3A Q9NY46 3/20 0.34
LMNA P02545 2/20 0.34
HRH1 P35367 2/20 0.34
CYP1A2 P05177 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
ADRA2A P08913 1/20 0.34
CYP2D6 P10635 1/20 0.34
CHRM1 P11229 1/20 0.34
ADRA2B P18089 1/20 0.34
CHRM3 P20309 1/20 0.34
SLC6A2 P23975 1/20 0.34
HRH2 P25021 1/20 0.34
HTR2C P28335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16618551 0.77 HTR2A (0.36) TSHRHTR2ATAAR1SCN1ASCN2A
SCHEMBL1230595 0.77 L3MBTL1 (0.42) TSHRHTR2ATAAR1SCN1ASCN2A
SCHEMBL30231920 0.76 SCN1A (0.50) TSHRHTR2ASCN1ASCN2ASCN3A
SCHEMBL3041553 0.76 SLC6A2 (0.47) TSHRCYP1A2CYP2D6SLC6A2SLC6A4
SCHEMBL11247443 0.74 TSHR (0.46) TSHRHTR2ATAAR1SCN1ASCN2A
SCHEMBL10006880 0.74 SCN4A (0.34) TSHRHTR2ATAAR1SCN1ASCN2A
SCHEMBL890872 0.74 HRH1 (0.45) TSHRHTR2ATAAR1SCN1ASCN2A
SCHEMBL28507818 0.74 NPSR1 (0.39) TSHRHTR2ATAAR1SCN1ASCN2A
SCHEMBL6239010 0.74 LMNA (0.43) TSHRHTR2ASCN1ASCN2ASCN3A
SCHEMBL10663765 0.73 TSHR (0.39) TSHRHTR2ATAAR1SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110033804-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-10 US disclosed
US-7001706-B2 Sulfonate and a resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-02-21 US disclosed
US-20050014095-A1 Sulfonate and a resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-01-20 US disclosed