SCHEMBL890872

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL891208	0.88	HRH1 (0.48)	HRH1TAAR1HTR2ACYP1A2CYP3A4
	SCHEMBL6239010	0.79	LMNA (0.43)	HRH1HTR2ACYP1A2TSHRKDM4E
	SCHEMBL7288351	0.78	SCN1A (0.57)	HRH1TAAR1HTR2ACYP1A2TSHR
	SCHEMBL16767872	0.78	HRH1 (0.48)	HRH1TAAR1HTR2ACYP1A2CYP3A4
	SCHEMBL8080315	0.76	LTA4H (0.44)	HRH1HTR2ACYP1A2TSHRKDM4E
	SCHEMBL4953952	0.76	SCN1A (0.38)	HRH1TAAR1HTR2ACYP1A2TSHR
	SCHEMBL10742649	0.75	HRH1 (0.45)	HRH1TAAR1HTR2ACYP1A2CYP3A4
	SCHEMBL891544	0.75	HTR2A (0.68)	HRH1HTR2ACYP1A2CYP3A4TSHR
	SCHEMBL2761483	0.75	LTA4H (0.44)	HTR2ACYP3A4TSHRALDH1A1MAPK1
	SCHEMBL1264057	0.74	TSHR (0.39)	HRH1TAAR1HTR2ACYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.