SCHEMBL1264286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1263980	0.87	NPC1 (0.42)	BCL2MCL1NPC1RAB9APTGS2
	SCHEMBL3762455	0.86	NPC1 (0.43)	NPC1RAB9AMAPTSMN1; SMN2LMNA
	SCHEMBL1264052	0.80	BCL2 (0.49)	BCL2MCL1NPC1RAB9APTGS1
	SCHEMBL1264010	0.78	NPC1 (0.45)	NPC1RAB9APTGS2MAPTSMN1; SMN2
	SCHEMBL1264001	0.78	NPC1 (0.45)	MCL1NPC1RAB9AMAPTSMN1; SMN2
	SCHEMBL1263991	0.78	NPC1 (0.40)	BCL2MCL1NPC1RAB9AMAPT
	SCHEMBL1263224	0.78	ALDH1A1 (0.40)	BCL2MCL1NPC1RAB9AMAPT
	SCHEMBL14323852	0.78	NPC1 (0.37)	NPC1RAB9AMAPTSMN1; SMN2LMNA
	SCHEMBL1263990	0.75	NPC1 (0.42)	NPC1RAB9AMAPTSMN1; SMN2LMNA
	SCHEMBL16135375	0.75	NPC1 (0.40)	NPC1RAB9AMAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.