Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263980 | 0.90 | NPC1 (0.42) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL1262808 | 0.87 | NPC1 (0.54) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL1264286 | 0.86 | BCL2 (0.37) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL1264001 | 0.81 | NPC1 (0.45) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL1264010 | 0.81 | NPC1 (0.45) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL1263991 | 0.81 | NPC1 (0.40) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL1263224 | 0.81 | ALDH1A1 (0.40) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL1263997 | 0.78 | NPC1 (0.58) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL1263990 | 0.78 | NPC1 (0.42) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Benzophenone SCHEMBL28090168 | 0.77 | ALOX5 (0.44) | NPC1RAB9APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847103-B2 | Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole | CHANG CHIA-HU | 2010-12-07 | — | — | US | claimed |