⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352247 | 0.79 | LDHA (0.50) | — | |
| SCHEMBL290730 | 0.73 | — | — | |
| SCHEMBL9509093 | 0.73 | LDHA (0.44) | — | |
| Hydrochloric Acid SCHEMBL4062946 | 0.71 | — | — | |
| Water SCHEMBL11546193 | 0.71 | — | — | |
| SCHEMBL27796812 | 0.71 | — | — | |
| SCHEMBL692743 | 0.71 | — | — | |
| SCHEMBL28332213 | 0.69 | LMNA (0.47) | — | |
| SCHEMBL3464176 | 0.69 | LMNA (0.47) | — | |
| SCHEMBL24241898 | 0.69 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9017673-B2 | Peptide analogues comprising at least one type of aminoacylaza-$g(b)<sp>3</sp>and the use thereof, in particular for therapy | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-04-28 | — | — | US | disclosed |
| US-8450284-B2 | Coiled-coil lipopeptide helical bundles and synthetic virus-like particles | UNIVERSITAET ZUERICH (CH) | 2013-05-28 | — | — | US | disclosed |
| US-8338393-B2 | Combination dosage forms and therapies for supporting bone health | PRIMUS PHARMACEUTICALS, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| EP-2121732-B1 | COILED-COIL LIPOPEPTIDE HELICAL BUNDLES AND SYNTHETIC VIRUS-LIKE PARTICLES | UNIV ZUERICH PROREKTORAT FORSCHUNG (CH) | 2012-07-04 | — | — | EP | disclosed |
| US-20110044974-A1 | Peptide analogues comprising at least one type of aminoacylaza-$g(b)<sp>3</sp>and the use thereof, in particular for therapy | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-02-24 | — | — | US | disclosed |
| US-20100015173-A1 | COILED-COIL LIPOPEPTIDE HELICAL BUNDLES AND SYNTHETIC VIRUS-LIKE PARTICLES | UNIVERSITÄT ZÓRICH PROREKTORAT FORSCHUNG (CH) | 2010-01-21 | — | — | US | disclosed |
| EP-2121732-A1 | COILED-COIL LIPOPEPTIDE HELICAL BUNDLES AND SYNTHETIC VIRUS-LIKE PARTICLES | Universität Zürich Prorektorat Forschung (CH) | 2009-11-25 | — | — | EP | disclosed |
| US-20090258845-A1 | Combination Dosage Forms and Therapies for Supporting Bone Health | PRIMUS PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| WO-2008068017-A1 | COILED-COIL LIPOPEPTIDE HELICAL BUNDLES AND SYNTHETIC VIRUS-LIKE PARTICLES | Universität Zürich Prorektorat Forschung (CH) | 2008-06-12 | — | — | WO | disclosed |
| EP-1631586-B1 | PEPTIDE ANALOGUES COMPRISING AT LEAST ONE TYPE OF AMINOACYL AZA-BETA 3 AND THE USE THEREOF, IN PARTICULAR FOR THERAPY | CENTRE NAT RECH SCIENT (FR) | 2007-08-22 | — | — | EP | disclosed |