Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.42 |
| ▸ | IL1B | P01584 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035793 | 0.85 | PTPN7 (0.42) | CNR2CNR1P2RX7IL1BPOLB | |
| SCHEMBL2040010 | 0.83 | CNR2 (0.48) | CNR2CNR1CECR2P2RX7IL1B | |
| SCHEMBL12643136 | 0.81 | NPSR1 (0.49) | CNR2CNR1P2RX7IL1BPOLB | |
| SCHEMBL12643148 | 0.80 | NPSR1 (0.51) | CNR2CNR1P2RX7IL1BPOLB | |
| SCHEMBL2034386 | 0.80 | CNR1 (0.47) | CNR2CNR1P2RX7IL1B | |
| SCHEMBL2038316 | 0.80 | P2RX7 (0.46) | CNR2CNR1P2RX7IL1B | |
| SCHEMBL12642978 | 0.79 | POLB (0.48) | CNR2CNR1P2RX7IL1BPOLB | |
| SCHEMBL2039992 | 0.78 | HTT (0.48) | CNR2CNR1 | |
| SCHEMBL12642984 | 0.78 | TDP1 (0.58) | P2RX7IL1BPOLBTDP1L3MBTL1 | |
| SCHEMBL12642947 | 0.78 | P2RX7 (0.47) | P2RX7IL1BPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079102-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2011-06-30 | — | — | WO | disclosed |