Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 7/20 | 0.48 |
| ▸ | GLA | P06280 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.43 |
| ▸ | IL1B | P01584 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643148 | 0.99 | NPSR1 (0.51) | NPSR1HSD17B10ALDH1A1KDM4EGAA | |
| SCHEMBL2039992 | 0.91 | HTT (0.48) | NPSR1HSD17B10ALDH1A1KDM4EGAA | |
| SCHEMBL2038550 | 0.84 | NPSR1 (0.54) | NPSR1HSD17B10ALDH1A1KDM4EGAA | |
| SCHEMBL12697362 | 0.84 | NPSR1 (0.54) | NPSR1HSD17B10ALDH1A1KDM4EGAA | |
| SCHEMBL2041723 | 0.83 | NPSR1 (0.56) | NPSR1HSD17B10ALDH1A1KDM4EGAA | |
| SCHEMBL12643149 | 0.81 | CNR2 (0.44) | P2RX7IL1BCNR1CNR2POLB | |
| SCHEMBL2039777 | 0.80 | NPSR1 (0.52) | NPSR1HSD17B10ALDH1A1KDM4EGAA | |
| SCHEMBL2034386 | 0.77 | CNR1 (0.47) | ALDH1A1P2RX7IL1BCNR1CNR2 | |
| SCHEMBL12642978 | 0.76 | POLB (0.48) | ALDH1A1HPGDP2RX7IL1BCNR1 | |
| SCHEMBL2034023 | 0.76 | NPSR1 (0.57) | NPSR1HSD17B10ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245161-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2012-09-27 | — | — | US | disclosed |
| WO-2011079102-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245161-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | TPSAB1, TPSB2, TPSD1 | NPSR1 49/4885HSD17B10 3797/4885ALDH1A1 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.