Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.65 |
| ▸ | LCK | P06239 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.56 |
| ▸ | PPID | Q08752 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035741 | 0.91 | PPID (0.64) | ATMLCKL3MBTL1NLRP3PPID | |
| SCHEMBL12643843 | 0.86 | ATM (0.64) | ATMLCKL3MBTL1PPIDPOLB | |
| SCHEMBL16270324 | 0.82 | ATM (0.65) | ATMLCKL3MBTL1NLRP3PPID | |
| SCHEMBL15832185 | 0.81 | PPID (0.65) | ATMLCKL3MBTL1PPIDPOLB | |
| SCHEMBL2561481 | 0.79 | ATM (1.00) | ATMLCKL3MBTL1POLBMAPT | |
| SCHEMBL10493865 | 0.79 | ATM (1.00) | ATMLCKL3MBTL1POLBMAPT | |
| SCHEMBL13505201 | 0.79 | ANPEP (0.56) | ATMLCKL3MBTL1PPIDPOLB | |
| SCHEMBL2041816 | 0.79 | PPID (0.53) | PPIDALDH1A1ANPEP | |
| SCHEMBL15623796 | 0.78 | ATM (0.87) | ATMLCKL3MBTL1POLBMAPT | |
| SCHEMBL14617737 | 0.78 | ATM (0.62) | ATMLCKL3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |