Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PPID | Q08752 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13505431 | 0.82 | ANPEP (0.63) | ANPEPALDH1A1ATML3MBTL1PPID | |
| SCHEMBL12643843 | 0.81 | ATM (0.64) | ANPEPALDH1A1ATML3MBTL1POLB | |
| SCHEMBL20241469 | 0.80 | TAAR1 (0.54) | ANPEPALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL13505312 | 0.80 | ALDH1A1 (0.43) | ANPEPALDH1A1ATML3MBTL1PPID | |
| SCHEMBL13505315 | 0.79 | PPARG (0.53) | ANPEPALDH1A1ATMSMN1; SMN2L3MBTL1 | |
| SCHEMBL12643839 | 0.79 | ATM (0.65) | ANPEPALDH1A1ATML3MBTL1POLB | |
| SCHEMBL12643953 | 0.77 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBPPIDKDM4E | |
| SCHEMBL2034518 | 0.77 | PPID (0.58) | ANPEPALDH1A1ATML3MBTL1POLB | |
| SCHEMBL29687069 | 0.76 | FPR2 (0.62) | ALDH1A1SMN1; SMN2POLBUSP2 | |
| SCHEMBL15832185 | 0.76 | PPID (0.65) | ANPEPALDH1A1ATMSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516387-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2012-10-31 | — | — | EP | disclosed |