SCHEMBL12644541

SCHEMBL12644541

COC(=O)CC[C@@H](C)C1CCC2C3CC[C@@H]4C[C@H](OC(C)=O)CC[C@]4(C)C3C[C@H](O)[C@@]21C

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.79
▸ MAPT P10636 2/20 0.79
▸ MEN1 O00255 2/20 0.79
▸ KMT2A Q03164 2/20 0.79
▸ LMNA P02545 1/20 0.79
▸ MAPK1 P28482 1/20 0.79
▸ VDR P11473 2/20 0.65
▸ GPBAR1 Q8TDU6 7/20 0.63
▸ NR1H4 Q96RI1 2/20 0.63
▸ SLC10A2 Q12908 2/20 0.63
▸ TBXA2R P21731 1/20 0.63
▸ PDE3A Q14432 1/20 0.63
▸ CYP2C9 P11712 1/20 0.61
▸ HIF1A Q16665 1/20 0.61
▸ CYP3A4 P08684 2/20 0.59
▸ SLCO1B3 Q9NPD5 1/20 0.59
▸ SLCO1B1 Q9Y6L6 1/20 0.59
▸ ABCC4 O15439 1/20 0.56
▸ CA1 P00915 1/20 0.54
▸ CA2 P00918 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14315480 1.00 USP2 (0.79) USP2MAPTMEN1KMT2ALMNA
SCHEMBL17578641 1.00 USP2 (0.79) USP2MAPTMEN1KMT2ALMNA
SCHEMBL17578745 1.00 USP2 (0.79) USP2MAPTMEN1KMT2ALMNA
SCHEMBL10073740 1.00 USP2 (0.79) USP2MAPTMEN1KMT2ALMNA
SCHEMBL330008 1.00 USP2 (0.79) USP2MAPTMEN1KMT2ALMNA
SCHEMBL17898400 1.00 USP2 (0.79) USP2MAPTMEN1KMT2ALMNA
SCHEMBL7992936 1.00 USP2 (0.79) USP2MAPTMEN1KMT2ALMNA
SCHEMBL12644507 0.95 USP2 (0.71) USP2MAPTMEN1KMT2ALMNA
SCHEMBL14570885 0.93 USP2 (0.79) USP2MAPTMEN1KMT2ALMNA
SCHEMBL5030971 0.93 USP2 (0.79) USP2MAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10981946-B2 Methods for the purification of deoxycholic acid ALLERGAN SALES, LLC (US) 2021-04-20 — — US disclosed
US-20200095274-A1 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID ALLERGAN SALES, LLC (US) 2020-03-26 — — US disclosed
US-10472384-B2 Methods for the purification of deoxycholic acid ALLERGAN SALES, LLC (US) 2019-11-12 — — US disclosed
EP-3138850-B1 COMPOSITIONS CONTAINING DEOXYCHOLIC ACID AND 10% DEIONIZED WATER IN ETHANOL, DIRECTED TO THE PURIFICATION OF DEOXYCHOLIC ACID KYTHERA BIOPHARMACEUTICALS INC (US) 2019-08-07 — — EP disclosed
US-20190135855-A1 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID KYTHERA BIOPHARMACEUTICALS, INC. (US) 2019-05-09 — — US disclosed
US-10005813-B2 Methods for the purification of deoxycholic acid KYTHERA BIOPHARMACEUTICALS, INC. (US) 2018-06-26 — — US disclosed
EP-2513132-B9 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID KYTHERA BIOPHARMACEUTICALS INC (US) 2017-12-27 — — EP disclosed
US-20170320905-A1 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID KYTHERA BIOPHARMACEUTICALS, INC. (US) 2017-11-09 — — US disclosed
US-9683007-B2 Methods for the purification of deoxycholic acid KYTHERA BIOPHARMACEUTICALS, INC. (US) 2017-06-20 — — US disclosed
EP-3138850-A1 COMPOSITIONS CONTAINING DEOXYCHOLIC ACID AND C1-3-ALCOHOLS, DIRECTED TO THE PURIFICATION OF DEOXYCHOLIC ACID Kythera Biopharmaceuticals, Inc. (US) 2017-03-08 — — EP disclosed
EP-2721047-B1 METHODS FOR THE SYNTHESIS AND PURIFICATION OF DEOXYCHOLIC ACID KYTHERA BIOPHARMACEUTICALS INC (US) 2016-11-16 — — EP disclosed
EP-3040342-A1 PURIFIED DEOXYCHOLIC ACID AND ITS COSMETIC USE IN THE NON-SURGICAL REMOVAL OF UNDESIRABLE FAT DEPOSITS Kythera Biopharmaceuticals, Inc. (US) 2016-07-06 — — EP disclosed
EP-2513132-B1 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID KYTHERA BIOPHARMACEUTICALS INC (US) 2016-03-09 — — EP disclosed
WO-2012174229-A2 METHODS FOR THE SYNTHESIS AND PURIFICATION OF DEOXYCHOLIC ACID KYTHERA BIOPHARMACEUTICALS, INC. (US) 2012-12-20 — — WO disclosed
WO-2011075701-A2 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID KYTHERA BIOPHARMACEUTICALS, INC. (US) 2011-06-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190135855-A1 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID HSD11B1, HSD17B7, HSD17B13 USP2 2008/4885MAPT 3484/4885MEN1 2399/4885
US-20200095274-A1 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID HSD11B1, HSD17B7, HSD17B13 USP2 2008/4885MAPT 3484/4885MEN1 2399/4885
US-10005813-B2 Methods for the purification of deoxycholic acid HSD11B1, HSD17B7, HSD17B13 USP2 2008/4885MAPT 3484/4885MEN1 2399/4885
US-10472384-B2 Methods for the purification of deoxycholic acid HSD11B1, HSD17B7, HSD17B13 USP2 2008/4885MAPT 3484/4885MEN1 2399/4885
US-10981946-B2 Methods for the purification of deoxycholic acid HSD11B1, HSD17B7, HSD17B13 USP2 2008/4885MAPT 3484/4885MEN1 2399/4885
US-20170320905-A1 METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID HSD11B1, HSD17B7, HSD17B13 USP2 2008/4885MAPT 3484/4885MEN1 2399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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