Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042273 | 0.82 | ITGB3 (0.39) | TLR4 | |
| SCHEMBL6440187 | 0.73 | — | — | |
| SCHEMBL2684077 | 0.68 | MME (0.36) | — | |
| SCHEMBL27705954 | 0.68 | RECQL (0.33) | RECQL | |
| SCHEMBL7622428 | 0.67 | MEN1 (0.34) | TLR4 | |
| SCHEMBL7619973 | 0.67 | FAAH (0.34) | — | |
| Hydrochloric Acid SCHEMBL27916784 | 0.66 | — | — | |
| SCHEMBL19831660 | 0.64 | CYP1A2 (0.39) | — | |
| SCHEMBL12646186 | 0.64 | ALOX15 (0.31) | — | |
| SCHEMBL13236674 | 0.64 | AKR1C4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937264-B1 | COMBINATION THERAPY FOR THE TREATMENT OF URINARY FREQUENCY, URINARY URGENCY AND URINARY INCONTINENCE | MERCK SHARP & DOHME (US) | 2011-06-08 | — | — | EP | disclosed |