SCHEMBL12646554

SCHEMBL12646554

C=Cc1nc2ccccc2cc1/C=C\C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.41
HPGD P15428 4/20 0.41
MAPT P10636 2/20 0.41
GLA P06280 1/20 0.41
ACHE P22303 1/20 0.41
TLR8 Q9NR97 3/20 0.40
GAA P10253 5/20 0.38
KDM4E B2RXH2 6/20 0.36
TDP1 Q9NUW8 1/20 0.36
STAT3 P40763 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 3/20 0.34
HTT P42858 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
PDE10A Q9Y233 1/20 0.34
TP53 P04637 1/20 0.34
SLC2A1 P11166 1/20 0.34
CYP1A2 P05177 3/20 0.33
CYP2C9 P11712 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12948126 0.87 ALDH1A1 (0.41) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL8594953 0.84 ALDH1A1 (0.48) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL18537211 0.83 TLR8 (0.50) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL23048973 0.79 ALDH1A1 (0.40) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL12646636 0.77 MAPT (0.39) ALDH1A1HPGDMAPTGAAKDM4E
SCHEMBL18537209 0.74 MEN1 (0.38) ALDH1A1HPGDMAPTGLAKDM4E
SCHEMBL7927941 0.74 TDP1 (0.52) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL14430830 0.73 TLR8 (0.47) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL27946755 0.72 ALDH1A1 (0.46) ALDH1A1HPGDMAPTGLAACHE
SCHEMBL2894808 0.72 ALDH1A1 (0.53) ALDH1A1HPGDMAPTGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828951-A1 ORGANIC ELECTRONIC DEVICE AND DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE AS WELL AS ORGANIC COMPOUNDS FOR USE IN ORGANIC ELECTRONIC DEVICES Novaled GmbH (DE) 2021-06-02 EP disclosed
US-7956020-B2 Reducing friction between two moving surfaces; oil additive mixture FUJIFILM CORPORATION (JP) 2011-06-07 US disclosed
US-20090143262-A1 Lubricant Composition FUJIFILM CORPORATION (JP) 2009-06-04 US disclosed
US-20090118146-A1 IMPREGNATING OIL COMPOSITION FOR SINTERED BEARING, BEARING APPARATUS AND SLIDING MEMBER FUJIFILM CORPORATION (JP) 2009-05-07 US disclosed
US-20080274920-A1 Reducing friction between two moving surfaces; oil additive mixture FUJIFILM CORPORATION (JP) 2008-11-06 US disclosed