SCHEMBL23048973

SCHEMBL23048973

C=Cc1nc2ccccc2cc1/C=N\C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.40
KDM4E B2RXH2 5/20 0.40
MAPT P10636 5/20 0.39
HPGD P15428 5/20 0.39
GLA P06280 1/20 0.39
ACHE P22303 1/20 0.39
GAA P10253 6/20 0.37
TLR8 Q9NR97 3/20 0.36
RAB9A P51151 6/20 0.36
NPC1 O15118 5/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
LMNA P02545 3/20 0.36
POLB P06746 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
STAT3 P40763 1/20 0.35
CYP1A2 P05177 4/20 0.33
PRKAG1 P54619 1/20 0.33
PRKAA1 Q13131 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8594953 0.83 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTHPGDGLA
SCHEMBL4233960 0.80 ALDH1A1 (0.52) ALDH1A1KDM4EMAPTHPGDGLA
SCHEMBL12646554 0.79 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTHPGDGLA
Hydrochloric Acid SCHEMBL4235429 0.78 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTHPGDGLA
SCHEMBL18537211 0.75 TLR8 (0.50) ALDH1A1KDM4EMAPTHPGDGLA
SCHEMBL12948126 0.72 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTHPGDGLA
SCHEMBL27946755 0.70 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTHPGDGLA
SCHEMBL2894808 0.70 ALDH1A1 (0.53) ALDH1A1KDM4EMAPTHPGDGLA
SCHEMBL27529586 0.70 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTHPGDGLA
SCHEMBL27961147 0.70 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTHPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2485289-B1 LAMINATED STRUCTURE, POLYMER, ELECTROLUMINESCENT ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT SUMITOMO CHEMICAL CO (JP) 2021-03-03 EP disclosed