Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12646554 | 0.83 | ALDH1A1 (0.41) | TLR8ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL8594953 | 0.80 | ALDH1A1 (0.48) | TLR8ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL23048973 | 0.75 | ALDH1A1 (0.40) | TLR8ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL12948126 | 0.73 | ALDH1A1 (0.41) | TLR8ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL982307 | 0.69 | ALDH1A1 (0.41) | TLR8ALDH1A1 | |
| SCHEMBL982304 | 0.69 | ALDH1A1 (0.41) | TLR8ALDH1A1 | |
| SCHEMBL2630610 | 0.69 | TLR8 (0.46) | TLR8ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL10337580 | 0.69 | ERN1 (0.38) | TLR8MEN1KMT2A | |
| SCHEMBL27529586 | 0.68 | ALDH1A1 (0.46) | TLR8ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL2894808 | 0.68 | ALDH1A1 (0.53) | TLR8ALDH1A1GAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133445-A1 | CHEMICALLY AMPLIFIED RESIST MATERIAL | OSAKA UNIVERSITY (JP) | 2017-02-22 | — | — | EP | disclosed |