⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14318100 | 0.74 | — | — | |
| SCHEMBL88454 | 0.74 | — | — | |
| SCHEMBL16716265 | 0.74 | — | — | |
| SCHEMBL18098502 | 0.72 | — | — | |
| SCHEMBL8092756 | 0.72 | ADH1B (0.41) | — | |
| SCHEMBL7678887 | 0.69 | — | — | |
| SCHEMBL8006800 | 0.69 | — | — | |
| SCHEMBL18488725 | 0.69 | — | — | |
| SCHEMBL8301690 | 0.67 | TRPA1 (0.38) | — | |
| SCHEMBL861760 | 0.67 | TRPA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118302-A1 | PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2011-05-19 | — | — | US | disclosed |
| US-7759376-B2 | Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity | BAYER HEALTHCARE LLC (US) | 2010-07-20 | — | — | US | disclosed |