Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.52 |
| ▸ | BHMT | Q93088 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75174 | 1.00 | SLC7A5 (0.52) | SLC7A5BHMTTDP1GABRPGABRD | |
| SCHEMBL2263294 | 1.00 | SLC7A5 (0.52) | SLC7A5BHMTTDP1GABRPGABRD | |
| SCHEMBL497652 | 1.00 | SLC7A5 (0.52) | SLC7A5BHMTTDP1GABRPGABRD | |
| SCHEMBL398726 | 1.00 | SLC7A5 (0.52) | SLC7A5BHMTTDP1GABRPGABRD | |
| SCHEMBL7411924 | 0.84 | SLC7A5 (0.46) | SLC7A5BHMTTDP1GABRPGABRD | |
| SCHEMBL14689821 | 0.83 | ALDH1A1 (0.38) | SLC7A5BHMTGABRPGABRDGABRA1 | |
| SCHEMBL24261803 | 0.83 | BHMT (0.40) | SLC7A5BHMTTDP1GABRPGABRD | |
| SCHEMBL5319867 | 0.83 | SLC7A5 (0.50) | SLC7A5BHMTKMT2ASLC1A3SLC1A2 | |
| SCHEMBL5319869 | 0.83 | SLC7A5 (0.50) | SLC7A5BHMTKMT2ASLC1A3SLC1A2 | |
| SCHEMBL10824295 | 0.83 | SLC7A5 (0.50) | SLC7A5BHMTKMT2ASLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140272066-A1 | GLUTAMIC ACID DERIVATIVES | GIVAUDAN SA (CH) | 2014-09-18 | — | — | US | disclosed |
| US-20140272066-A1 | GLUTAMIC ACID DERIVATIVES | GIVAUDAN SA (CH) | 2014-09-18 | — | — | US | disclosed |
| US-8569481-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PHARMACEUTICALS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | KOESTER HUBERT | 2011-05-19 | — | — | US | disclosed |
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-11-25 | — | — | US | disclosed |
| US-20100248264-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PTMS, QPCTL, SRMS | SLC7A5 1848/4885BHMT 3844/4885TDP1 2627/4885 |
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CHLSN, PTMS, SRMS | SLC7A5 3966/4885BHMT 2941/4885TDP1 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.