Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | BLM | P54132 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | RGS12 | O14924 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | THPO | P40225 | 2/20 | 0.60 |
| ▸ | MTOR | P42345 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175613 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTMEN1CYP3A4TSHR | |
| SCHEMBL11141872 | 0.80 | HTT (0.61) | SMN1; SMN2MAPTMEN1CYP3A4TSHR | |
| SCHEMBL28419449 | 0.80 | EGFR (0.63) | SMN1; SMN2MAPTMEN1CYP3A4TSHR | |
| SCHEMBL14472045 | 0.78 | HTT (0.63) | SMN1; SMN2MAPTMEN1CYP3A4TSHR | |
| SCHEMBL1821479 | 0.78 | PTGS1 (0.74) | SMN1; SMN2MAPTMEN1CYP3A4TSHR | |
| SCHEMBL1821480 | 0.78 | PTGS1 (0.74) | SMN1; SMN2MAPTMEN1CYP3A4TSHR | |
| SCHEMBL13073158 | 0.77 | GABBR2 (0.63) | SMN1; SMN2MAPTMEN1CYP3A4TSHR | |
| Tyrphostin Ag 879 SCHEMBL607701 | 0.76 | MAPT (1.00) | SMN1; SMN2MAPTMEN1CYP3A4TSHR | |
| Tyrphostin Ag 879 SCHEMBL607702 | 0.76 | MAPT (1.00) | SMN1; SMN2MAPTMEN1CYP3A4TSHR | |
| Tyrphostin Ag 879 SCHEMBL607703 | 0.76 | MAPT (1.00) | SMN1; SMN2MAPTMEN1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | KOESTER HUBERT | 2011-05-19 | — | — | US | disclosed |
| US-20100248264-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PTMS, QPCTL, SRMS | SMN1; SMN2 4623/4885MAPT 3419/4885MEN1 3426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.