Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICOSLG | O75144 | 1/20 | 0.35 |
| ▸ | ICOS | Q9Y6W8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12619799 | 0.91 | ICOSLG (0.45) | ICOSLGICOS | |
| SCHEMBL12653368 | 0.81 | ICOSLG (0.45) | ICOSLGICOS | |
| SCHEMBL1801702 | 0.78 | ICOSLG (0.61) | ICOSLGICOS | |
| SCHEMBL12619440 | 0.78 | ICOSLG (0.61) | ICOSLGICOS | |
| SCHEMBL12619474 | 0.78 | ICOSLG (0.44) | ICOSLGICOS | |
| SCHEMBL12619473 | 0.78 | ICOSLG (0.44) | ICOSLGICOS | |
| SCHEMBL12653326 | 0.77 | ICOSLG (0.34) | ICOSLGICOS | |
| SCHEMBL12619673 | 0.77 | ICOSLG (0.43) | ICOSLGICOS | |
| SCHEMBL1810096 | 0.76 | ICOSLG (0.45) | ICOSLGICOS | |
| SCHEMBL13349318 | 0.75 | ICOSLG (0.53) | ICOSLGICOS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951801-B2 | For therapy of inflammatory disease and cancer | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-05-31 | — | — | US | disclosed |