Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 3/20 | 0.51 |
| ▸ | ICOSLG | O75144 | 2/20 | 0.51 |
| ▸ | ICOS | Q9Y6W8 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803613 | 0.81 | CHUK (0.77) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL1798941 | 0.69 | CHUK (0.84) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL1420073 | 0.67 | CHUK (1.00) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL30039188 | 0.67 | CHUK (1.00) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL30342072 | 0.67 | CHUK (1.00) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL30492167 | 0.67 | CHUK (1.00) | CHUKICOSLGICOSIKBKBTYK2 | |
| Hydrochloric Acid SCHEMBL18114522 | 0.67 | CHUK (0.98) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL1797398 | 0.67 | CHUK (0.77) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL25480675 | 0.65 | ICOSLG (0.66) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL17225471 | 0.64 | CHUK (0.81) | CHUKICOSLGICOSIKBKBTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951801-B2 | For therapy of inflammatory disease and cancer | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-05-31 | — | — | US | disclosed |