⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695287 | 0.80 | — | — | |
| SCHEMBL18207641 | 0.80 | — | — | |
| SCHEMBL3115140 | 0.80 | — | — | |
| SCHEMBL8766553 | 0.80 | — | — | |
| SCHEMBL3559815 | 0.78 | TSHR (0.43) | — | |
| SCHEMBL1808716 | 0.76 | GABRA1 (0.46) | — | |
| SCHEMBL396284 | 0.76 | GABRA1 (0.56) | — | |
| SCHEMBL7192125 | 0.74 | ALDH1A1 (0.50) | — | |
| SCHEMBL22686100 | 0.74 | MYC (0.52) | — | |
| SCHEMBL3094328 | 0.71 | CYP2A6 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2684 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111433231-B | Method for producing styrene resin and styrene resin molded body | 出光兴产株式会社 | 2024-07-16 | — | — | CN | claimed |
| US-20230310454-A1 | RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | RIGEL PHARMACEUTICALS, INC. | 2023-10-05 | — | — | US | claimed |
| CN-116726996-A | Catalyst for isomerization of branched unsaturated fatty nitrile, preparation method and application thereof | 北京旭阳科技有限公司 | 2023-09-12 | — | — | CN | claimed |
| US-11564930-B2 | RIP1 inhibitory compounds and methods for making and using the same | RIGEL PHARMACEUTICALS, INC. (US) | 2023-01-31 | — | — | US | claimed |
| CN-115279763-A | RIP1 inhibiting compounds and methods of making and using the same | 里格尔药品股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| EP-4025575-A1 | RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | Rigel Pharmaceuticals, Inc. (US) | 2022-07-13 | — | — | EP | claimed |
| EP-4025574-A1 | RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | Rigel Pharmaceuticals, Inc. (US) | 2022-07-13 | — | — | EP | claimed |
| EP-4025568-A1 | RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | Rigel Pharmaceuticals, Inc. (US) | 2022-07-13 | — | — | EP | claimed |
| CN-114728958-A | RIP1 inhibiting compounds and methods of making and using the same | 里格尔药品股份有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-114728918-A | RIP1 inhibiting compounds and methods of making and using the same | 里格尔药品股份有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-1191223-A | Catalyst system for syndiotactic polymerization, its preparing method and use thereof | CHINESE ACAD INST CHEMISTRY (CN) | 1998-08-26 | — | — | CN | claimed |
| US-5753780-A | ALPHA TO A PHENYL RING, COBALT OXIDATION CATALYST | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-05-19 | — | — | US | claimed |
| US-5721350-A | Deuterated nucleosides | CHATTOPADHYAYA JYOTI (SE) | 1998-02-24 | — | — | US | claimed |
| EP-0699200-B1 | DIHALOTRIAZOLOPYRIMIDINE DERIVATIVES AS FUNGICIDES | SHELL INT RESEARCH (NL) | 1997-10-29 | — | — | EP | claimed |
| US-5468814-A | Catalytic oxidation of benzylic carbon atoms pendant from phenyl rings of precursor polymer, forming aldehyde and acid groups | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-11-21 | — | — | US | claimed |
| EP-0666873-A1 | POLYMERS HAVING OXIDIC FUNCTIONALITY AND DERIVATIVES THEREOF | RESEARCH CORPORATION TECHNOLOGIES (US) | 1995-08-16 | — | — | EP | claimed |
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | claimed |
| WO-1994010215-A1 | POLYMERS HAVING OXIDIC FUNCTIONALITY AND DERIVATIVES THEREOF | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-05-11 | — | — | WO | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
| US-4244731-A | APPLYING A CARBOXY DERIVATIVE OF A 2,6-DIMETHYLPHENOXY COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-01-13 | — | — | US | claimed |