⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126537 | 0.80 | — | — | |
| SCHEMBL330593 | 0.80 | — | — | |
| SCHEMBL12792 | 0.77 | — | — | |
| SCHEMBL29432874 | 0.77 | — | — | |
| SCHEMBL14127455 | 0.77 | — | — | |
| SCHEMBL292927 | 0.75 | CYP1A2 (0.54) | — | |
| 1,2-Dichlorobenzene SCHEMBL521767 | 0.75 | TSHR (0.62) | — | |
| SCHEMBL31131455 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL9527099 | 0.75 | — | — | |
| SCHEMBL28873613 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442972-A1 | BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2019-02-20 | — | — | EP | claimed |
| WO-2017177955-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC. (US) | 2017-10-19 | — | — | WO | claimed |
| US-20100179109-A1 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. | 2010-07-15 | — | — | US | claimed |
| WO-2008124575-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | claimed |
| EP-3442972-A1 | BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017177955-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC. (US) | 2017-10-19 | — | — | WO | disclosed |
| CN-102083799-B | Benzimidazole derivatives used as FXR agonists | HOFFMANN LA ROCHE | 2013-10-16 | — | — | CN | disclosed |
| CN-102083799-A | Benzimidazole derivatives used as FXR agonists | HOFFMANN LA ROCHE | 2011-06-01 | — | — | CN | disclosed |
| US-20100179109-A1 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. | 2010-07-15 | — | — | US | disclosed |
| US-20090306376-A1 | OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME | MITSUI CHEMICALS, INC. (JP) | 2009-12-10 | — | — | US | disclosed |
| WO-2008124575-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |
| US-20070054084-A1 | Optical recording medium and compound used for the same | MITSUI CHEMICALS, INC. (JP) | 2007-03-08 | — | — | US | disclosed |
| US-4033949-A | Analogs of thromboxane B2 and processes for their synthesis | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4029681-A | 13,14-Didehydro-PG analogs | THE UPJOHN COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4028419-A | PROSTAGLANDINS | THE UPJOIN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4028350-A | ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4026909-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-05-31 | — | — | US | disclosed |
| US-4018803-A | 13,14-Didehydro-PG3 compounds | THE UPJOHN COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |