Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22845470 | 0.86 | OPRK1 (0.47) | MEN1KMT2AOPRK1OPRM1LMNA | |
| SCHEMBL22845474 | 0.82 | SMN1; SMN2 (0.44) | OPRK1LMNACYP2D6SMN1; SMN2TRPA1 | |
| SCHEMBL12672377 | 0.81 | ESR1 (0.46) | MMP9MMP8ESR1MEN1KMT2A | |
| SCHEMBL12672526 | 0.80 | BLM (0.46) | MMP9MMP8ESR1MEN1KMT2A | |
| SCHEMBL14469645 | 0.74 | OPRK1 (0.47) | MEN1KMT2AOPRK1OPRM1LMNA | |
| SCHEMBL7176489 | 0.73 | SMN1; SMN2 (0.70) | MMP9MMP8MEN1KMT2AOPRK1 | |
| SCHEMBL4424042 | 0.73 | SMN1; SMN2 (0.70) | MMP9MMP8MEN1KMT2AOPRK1 | |
| SCHEMBL9089267 | 0.73 | SMN1; SMN2 (0.70) | MMP9MMP8MEN1KMT2AOPRK1 | |
| SCHEMBL9135588 | 0.73 | LMNA (0.57) | MMP8OPRK1OPRM1OPRD1LMNA | |
| SCHEMBL10087162 | 0.72 | LMNA (0.61) | MMP8OPRK1OPRM1OPRD1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011053835-A1 | STEREOSELECTIVE SYNTHESIS OF METYROSINE | ATON PHARMA, INC. (US) | 2011-05-05 | — | — | WO | disclosed |