SCHEMBL10087162

SCHEMBL10087162

CC(C)NC(C)(C)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.61
CYP2D6 P10635 1/20 0.61
TRPA1 O75762 1/20 0.48
TAAR1 Q96RJ0 3/20 0.48
SLC6A2 P23975 1/20 0.48
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ADRB2 P07550 2/20 0.41
SLC18A2 Q05940 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
OPRK1 P41145 2/20 0.40
MMP8 P22894 2/20 0.40
OPRM1 P35372 1/20 0.40
OPRD1 P41143 1/20 0.40
CACNA1F O60840 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
ADRA2B P18089 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9135588 0.84 LMNA (0.57) LMNACYP2D6TRPA1TAAR1SLC6A2
SCHEMBL10087170 0.80 CASR (0.44) LMNACYP2D6TRPA1TAAR1ADRB2
SCHEMBL29766278 0.80 LMNA (0.57) LMNACYP2D6TRPA1TAAR1SLC6A2
SCHEMBL9135600 0.80 TRPA1 (0.50) LMNACYP2D6TRPA1TAAR1SLC6A2
SCHEMBL29587381 0.80 CYP2D6 (0.47) LMNACYP2D6CYP3A4SIGMAR1CASR
SCHEMBL16589312 0.78 CASR (0.53) CASR
SCHEMBL13996918 0.77 CASR (0.57) ALDH1A1ADRB2CASR
SCHEMBL14161468 0.77 LMNA (0.63) LMNACYP2D6TRPA1TAAR1SLC6A2
SCHEMBL11818840 0.77 LMNA (0.63) LMNACYP2D6TRPA1TAAR1SLC6A2
SCHEMBL23901642 0.76 ENPEP (0.48) LMNACYP2D6TRPA1TAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106796401-A Pattern forming method, composition for forming upper layer film, resist pattern, and method for manufacturing electronic device 富士胶片株式会社 2017-05-31 CN disclosed
CN-106716257-A Pattern forming method, resist pattern, and electronic device manufacturing method 富士胶片株式会社 2017-05-24 CN disclosed
CN-106605174-A Pattern forming method, composition for forming protective film, method for manufacturing electronic component, and electronic component 富士胶片株式会社 2017-04-26 CN disclosed
CN-103619947-A Active energy ray-curable coating resin composition KANEKA CORP 2014-03-05 CN disclosed
US-8124634-B2 CB1 receptor modulators 7TM PHARMA A/S (DK) 2012-02-28 US disclosed
US-7888363-B2 1-Cyclopentyl-3-methyl-2-(2-pyridyl)indole-5-amino/thio/carbonyl derivatives; hepatitis C virus infection; synergistic with another inhibitor of HCV polymerase or immunomodulatory agent such as interferons BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-02-15 US disclosed
US-20100010061-A1 CB1 RECEPTOR MODULATORS 7TM PHARMA A/S (DK) 2010-01-14 US disclosed
US-20070142380-A1 Viral Polymerase Inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-06-21 US disclosed
US-7223785-B2 Viral polymerase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142380-A1 Viral Polymerase Inhibitors POLM, POLR2H, POLR2A LMNA 2179/4885CYP2D6 865/4885TRPA1 2999/4885
US-20100010061-A1 CB1 RECEPTOR MODULATORS CNR1, CNR2, GPR6 LMNA 4443/4885CYP2D6 893/4885TRPA1 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.