Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16716228 | 0.97 | MAOA (0.37) | NPC1RAB9ASMN1; SMN2TDP1HPGD | |
| SCHEMBL16716235 | 0.94 | SMN1; SMN2 (0.36) | NPC1RAB9ASMN1; SMN2TDP1HPGD | |
| SCHEMBL15860822 | 0.89 | NOS2 (0.41) | NPC1RAB9ASMN1; SMN2HPGDNOS2 | |
| SCHEMBL24752556 | 0.87 | CKS1B (0.35) | NPC1RAB9ASMN1; SMN2TDP1HPGD | |
| SCHEMBL19534168 | 0.86 | CYP1A2 (0.43) | SMN1; SMN2HPGDNOS2LMNANR1H2 | |
| SCHEMBL18960590 | 0.84 | HPGD (0.38) | NPC1RAB9ASMN1; SMN2TDP1HPGD | |
| SCHEMBL18562484 | 0.84 | NOS2 (0.36) | NPC1RAB9ASMN1; SMN2NOS2LMNA | |
| SCHEMBL19315263 | 0.84 | ALDH1A1 (0.40) | NPC1RAB9ASMN1; SMN2TDP1HPGD | |
| SCHEMBL19534098 | 0.83 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2TDP1HPGD | |
| SCHEMBL19688289 | 0.81 | TAAR1 (0.37) | NPC1RAB9ASMN1; SMN2TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055912-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2011-05-12 | — | — | WO | disclosed |