Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12333231 | 0.82 | HDAC8 (0.49) | ALDH1A1MEN1HPGDKMT2ACYP1A2 | |
| SCHEMBL22779244 | 0.82 | ALOX5 (0.47) | SOS1HPRT1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL12014580 | 0.80 | ALDH1A1 (0.46) | SOS1HPRT1ALDH1A1MEN1HPGD | |
| SCHEMBL12014564 | 0.79 | ALDH1A1 (0.45) | SOS1HPRT1ALDH1A1MEN1HPGD | |
| SCHEMBL12655569 | 0.79 | HDAC4 (0.37) | SOS1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL12655934 | 0.78 | SOS1 (0.41) | SOS1HPRT1ALDH1A1MEN1HPGD | |
| SCHEMBL12655785 | 0.78 | NPC1 (0.39) | SOS1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL24689595 | 0.78 | HDAC8 (0.42) | CYP1A2CYP2C9CYP2C19HDAC4HDAC2 | |
| SCHEMBL27047246 | 0.78 | HPRT1 (0.48) | SOS1HPRT1ALDH1A1MEN1HPGD | |
| SCHEMBL17268970 | 0.78 | HPRT1 (0.48) | SOS1HPRT1ALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011054442-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | WO | disclosed |