Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14681221 | 0.81 | ITGB3 (0.49) | TDP1PPARA | |
| SCHEMBL8435205 | 0.80 | TDP1 (0.46) | TDP1LTA4HPPARAPARP10HPGD | |
| SCHEMBL14681222 | 0.78 | GRIK1 (0.64) | GRM2GRM3GRIK1 | |
| SCHEMBL12656179 | 0.77 | LTA4H (0.60) | LTA4HPPARA | |
| SCHEMBL6819996 | 0.76 | LTA4H (0.45) | TDP1LTA4HPPARAPARP10HPGD | |
| SCHEMBL18019364 | 0.76 | SLC1A1 (0.38) | TDP1LTA4HGRIK1 | |
| SCHEMBL15984257 | 0.76 | SLC1A2 (0.53) | GRIK1 | |
| SCHEMBL18019367 | 0.75 | SLC1A2 (0.33) | GRIK1 | |
| SCHEMBL11566290 | 0.75 | LTA4H (0.46) | TDP1LTA4H | |
| Hydrochloric Acid SCHEMBL8129682 | 0.74 | SLC1A1 (0.64) | LTA4HGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061154-A1 | IODINE-LABELED HOMOGLUTAMIC ACID AND GLUTAMIC ACID DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-26 | — | — | WO | disclosed |