Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15986736 | 0.84 | DUT (0.34) | DUTMEN1GAAKMT2A | |
| SCHEMBL13639864 | 0.80 | SLC1A1 (0.55) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL15984257 | 0.79 | SLC1A2 (0.53) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL18019364 | 0.79 | SLC1A1 (0.38) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL28580283 | 0.76 | GSR (0.43) | NOS1NOS3NOS2MEN1KMT2A | |
| SCHEMBL4217873 | 0.76 | NOS1 (0.33) | NOS1NOS3NOS2KMT2A | |
| SCHEMBL12656010 | 0.75 | TDP1 (0.49) | GRIK1 | |
| SCHEMBL7365588 | 0.74 | DUT (0.33) | DUTMEN1GAAKMT2A | |
| SCHEMBL1067514 | 0.73 | IDO1 (0.34) | SLC1A1 | |
| SCHEMBL30980082 | 0.73 | IDO1 (0.34) | SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2705011-B1 | NOVEL PRECURSORS OF GLUTAMATE DERIVATIVES | PIRAMAL IMAGING SA (CH) | 2016-08-17 | — | — | EP | disclosed |