Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 6/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223874 | 0.83 | KDM4E (0.40) | KDM4EASPHKDM8KCNQ3KCNQ2 | |
| SCHEMBL30770791 | 0.81 | HSP90AB1 (0.37) | KDM4ETSHRHSP90AB1KCNQ3KCNQ2 | |
| SCHEMBL27334085 | 0.81 | HSP90AB1 (0.37) | KDM4ETSHRHSP90AB1KCNQ3KCNQ2 | |
| SCHEMBL1809928 | 0.80 | KDM4E (0.43) | KDM4EASPHKDM8KCNQ3KCNQ2 | |
| SCHEMBL28824877 | 0.80 | KDM4E (0.46) | KDM4EASPHKDM8KCNQ3KCNQ2 | |
| SCHEMBL16712886 | 0.79 | GABRP (0.37) | KDM4EHSP90AB1ALDH1A1HMGCRMAPT | |
| SCHEMBL21530434 | 0.79 | JMJD6 (0.56) | KDM4ETSHRJMJD6ALDH1A1MAPT | |
| SCHEMBL20073627 | 0.79 | NNMT (0.40) | KDM4ETSHRHSP90AB1ALDH1A1HMGCR | |
| SCHEMBL29947373 | 0.79 | NNMT (0.40) | KDM4ETSHRHSP90AB1ALDH1A1HMGCR | |
| SCHEMBL29813883 | 0.78 | ASPH (0.63) | KDM4EASPHKDM8TSHRKCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |