Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919819 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL959122 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL960179 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL959075 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL19834295 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL959179 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL19834263 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL15906663 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL78821 | 0.75 | CYP2C9 (0.68) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL38819 | 0.75 | CYP2C9 (0.68) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105481-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | PAIN THERAPEUTICS | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105481-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | FLNA, FLNB, OPRK1 | ALDH1A1 2575/4885HSD17B10 4550/4885CASP1 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.