Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21164212 | 0.76 | TGM2 (0.47) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL14864328 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL156493 | 0.69 | ALDH1A1 (0.63) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL21907075 | 0.69 | ALDH1A1 (0.41) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL7640295 | 0.68 | ALDH1A1 (0.61) | ALDH1A1HCAR2MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL17779954 | 0.67 | ALDH1A1 (0.50) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL22716123 | 0.67 | ALDH1A1 (0.59) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL14465543 | 0.67 | ALDH1A1 (0.46) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL9926611 | 0.67 | ALDH1A1 (0.59) | ALDH1A1HCAR2CA12CA1CA2 | |
| Propane SCHEMBL28845720 | 0.67 | ALDH1A1 (0.59) | ALDH1A1HCAR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633724-B1 | PHTHALAZINONE DERIVATIVES | KUDOS PHARM LTD (GB) | 2011-05-04 | — | — | EP | disclosed |