Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658016 | 0.90 | SLC6A4 (0.37) | HTR2AKCNH2SLC6A4KDM4ELMNA | |
| SCHEMBL12658219 | 0.86 | KDM4E (0.38) | HTR2AKCNH2SLC6A4KDM4ELMNA | |
| SCHEMBL14188729 | 0.83 | KDM4E (0.46) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL12658116 | 0.81 | NR4A2 (0.44) | HTR2ASLC6A4KDM4EMEN1KMT2A | |
| SCHEMBL12658117 | 0.80 | NR4A2 (0.45) | SLC6A4KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL12658216 | 0.79 | TDO2 (0.41) | HTR2AKCNH2 | |
| SCHEMBL12658122 | 0.78 | MAPT (0.49) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL12658120 | 0.77 | NR4A2 (0.55) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL12658121 | 0.75 | IGF1R (0.37) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL12658025 | 0.74 | ALPL (0.49) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711486-B1 | BIS-INDOLE PYRROLES USEFUL AS ANTIMICROBIAL AGENTS | NEREUS PHARMACEUTICALS INC (US) | 2011-05-11 | — | — | EP | disclosed |