Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658024 | 0.94 | F7 (0.59) | F7F3MAP2NR4A2NHERF1 | |
| Lynamicin B SCHEMBL12658014 | 0.86 | NR4A2 (0.55) | F7F3NR4A2 | |
| SCHEMBL12658119 | 0.83 | TSHR (0.47) | F7F3NR4A2NHERF1 | |
| SCHEMBL12658020 | 0.81 | F7 (0.60) | F7F3MAP2NR4A2NHERF1 | |
| SCHEMBL12658279 | 0.81 | KDM4E (0.47) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL14215588 | 0.80 | F7 (0.49) | F7F3NR4A2HTR2A | |
| Lynamicin A SCHEMBL12658027 | 0.79 | NR4A2 (0.61) | F7F3NR4A2 | |
| SCHEMBL12658136 | 0.78 | F7 (0.45) | F7F3MAP2NR4A2NHERF1 | |
| SCHEMBL12658130 | 0.78 | NR4A2 (0.51) | F7F3PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL5427525 | 0.76 | F7 (0.64) | F7F3NR4A2NHERF1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711486-B1 | BIS-INDOLE PYRROLES USEFUL AS ANTIMICROBIAL AGENTS | NEREUS PHARMACEUTICALS INC (US) | 2011-05-11 | — | — | EP | disclosed |
| US-7375129-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375129-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-20070149601-A1 | Bis-indole pyrroles useful as antimicrobials agents | PRIVATE LIFE BIOMED AG (DE) | 2007-06-28 | — | — | US | disclosed |
| US-20070149601-A1 | Bis-indole pyrroles useful as antimicrobials agents | PRIVATE LIFE BIOMED AG (DE) | 2007-06-28 | — | — | US | disclosed |
| US-7166634-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166634-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2007-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149601-A1 | Bis-indole pyrroles useful as antimicrobials agents | IDO1, IDO2, TPH1 | F7 4043/4885F3 3673/4885PRKAB2 4019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.