Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | MAP2 | P11137 | 1/20 | 0.38 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658026 | 0.88 | NR4A2 (0.48) | F7F3NR4A2MEN1ALDH1A1 | |
| SCHEMBL12658015 | 0.86 | F7 (0.42) | F7F3MAP2NHERF1NR4A2 | |
| SCHEMBL12658283 | 0.85 | TSHR (0.42) | F7F3NHERF1NR4A2GABRP | |
| SCHEMBL12658024 | 0.84 | F7 (0.59) | F7F3MAP2NHERF1NR4A2 | |
| SCHEMBL12658207 | 0.81 | NR4A2 (0.45) | F7F3NR4A2MEN1ALDH1A1 | |
| SCHEMBL12658131 | 0.78 | F7 (0.52) | F7F3MAP2NHERF1NR4A2 | |
| SCHEMBL12658121 | 0.77 | IGF1R (0.37) | NR4A2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12658020 | 0.75 | F7 (0.60) | F7F3MAP2NHERF1NR4A2 | |
| SCHEMBL12658115 | 0.75 | NR4A2 (0.45) | F7F3NR4A2HTR2AMEN1 | |
| SCHEMBL12658126 | 0.72 | NR4A2 (0.44) | F7F3NR4A2HTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711486-B1 | BIS-INDOLE PYRROLES USEFUL AS ANTIMICROBIAL AGENTS | NEREUS PHARMACEUTICALS INC (US) | 2011-05-11 | — | — | EP | disclosed |