Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.60 |
| ▸ | F3 | P13726 | 1/20 | 0.60 |
| ▸ | MAP2 | P11137 | 3/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658024 | 0.87 | F7 (0.59) | F7F3MAP2NR4A2NHERF1 | |
| Lynamicin D SCHEMBL12658118 | 0.83 | NR4A2 (0.63) | F7F3NR4A2 | |
| SCHEMBL12658131 | 0.81 | F7 (0.52) | F7F3MAP2NR4A2NHERF1 | |
| SCHEMBL5427525 | 0.79 | F7 (0.64) | F7F3NR4A2NHERF1GPR84 | |
| Lynamicin E SCHEMBL12658018 | 0.79 | NR4A2 (0.56) | MAP2NR4A2GPR84 | |
| Lycogalic Acid A SCHEMBL12955978 | 0.78 | ALDH1A1 (0.54) | GPR84 | |
| Lycogalic Acid A SCHEMBL29465596 | 0.78 | ALDH1A1 (0.54) | GPR84 | |
| SCHEMBL12658120 | 0.78 | NR4A2 (0.55) | F7F3MAP2NR4A2 | |
| SCHEMBL1434913 | 0.76 | F7 (1.00) | F7F3NR4A2NHERF1GPR84 | |
| SCHEMBL12658136 | 0.75 | F7 (0.45) | F7F3MAP2NR4A2NHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711486-B1 | BIS-INDOLE PYRROLES USEFUL AS ANTIMICROBIAL AGENTS | NEREUS PHARMACEUTICALS INC (US) | 2011-05-11 | — | — | EP | disclosed |
| US-7375129-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375129-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-20070149601-A1 | Bis-indole pyrroles useful as antimicrobials agents | PRIVATE LIFE BIOMED AG (DE) | 2007-06-28 | — | — | US | disclosed |
| US-20070149601-A1 | Bis-indole pyrroles useful as antimicrobials agents | PRIVATE LIFE BIOMED AG (DE) | 2007-06-28 | — | — | US | disclosed |
| US-7166634-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166634-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2007-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149601-A1 | Bis-indole pyrroles useful as antimicrobials agents | IDO1, IDO2, TPH1 | F7 4043/4885F3 3673/4885MAP2 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.