Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658114 | 0.91 | SPR (0.42) | SPRNOTUMMTNR1AMTNR1BMPO | |
| SCHEMBL14188731 | 0.89 | SPR (0.41) | SPRNOTUMMTNR1AMTNR1BMPO | |
| SCHEMBL14215657 | 0.87 | KDM4E (0.46) | SPRNOTUMMTNR1AMTNR1BMPO | |
| SCHEMBL14188730 | 0.86 | NR4A2 (0.54) | SPRNOTUMMTNR1AMTNR1BNR4A2 | |
| SCHEMBL12658205 | 0.81 | NR4A2 (0.44) | MTNR1AMTNR1BNR4A2SLC6A4PRKAB2 | |
| Lynamicin B SCHEMBL12658014 | 0.80 | NR4A2 (0.55) | MTNR1AMTNR1BNR4A2KDM4E | |
| SCHEMBL14188735 | 0.79 | NR4A2 (0.52) | MTNR1AMTNR1BTSHRNR4A2KDM4E | |
| SCHEMBL12658130 | 0.79 | NR4A2 (0.51) | MTNR1AMTNR1BNR4A2KDM4EHTR7 | |
| Lynamicin A SCHEMBL12658027 | 0.79 | NR4A2 (0.61) | MTNR1AMTNR1BNR4A2KDM4E | |
| SCHEMBL14188729 | 0.77 | KDM4E (0.46) | SPRNOTUMMTNR1AMTNR1BMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711486-B1 | BIS-INDOLE PYRROLES USEFUL AS ANTIMICROBIAL AGENTS | NEREUS PHARMACEUTICALS INC (US) | 2011-05-11 | — | — | EP | disclosed |