SCHEMBL12658256

SCHEMBL12658256

NOc1cc2ccccc2cc1C(=O)N(N)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
IDO1 P14902 1/20 0.41
IRAK4 Q9NWZ3 1/20 0.41
TDP1 Q9NUW8 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAOB P27338 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
ATR Q13535 1/20 0.36
MYC P01106 1/20 0.36
KMT2A Q03164 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 2/20 0.35
MITF O75030 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
NCOA1 Q15788 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769555 0.73 NPSR1 (0.52) HPGDKDM4EALDH1A1TDP1ATM
SCHEMBL11848661 0.72 ESR1 (0.59) HPGDKDM4EALDH1A1TDP1KMT2A
SCHEMBL11833560 0.70 NR4A1 (0.58) HPGDKDM4EALDH1A1TDP1L3MBTL1
Hydrochloric Acid SCHEMBL11865419 0.69 NR4A1 (0.56) HPGDKDM4EALDH1A1TDP1L3MBTL1
SCHEMBL9769553 0.69 ALDH1A1 (0.58) HPGDKDM4EALDH1A1TDP1ATM
SCHEMBL407836 0.68 L3MBTL1 (0.50) HPGDKDM4EALDH1A1TDP1L3MBTL1
SCHEMBL10949416 0.68 NPSR1 (0.50) HPGDKDM4EALDH1A1TDP1L3MBTL1
Anthracene SCHEMBL28274691 0.67 IDO1 (0.48) HPGDKDM4EALDH1A1IDO1IRAK4
SCHEMBL28147856 0.67 KDM4E (0.56) HPGDKDM4EALDH1A1TDP1L3MBTL1
SCHEMBL14328976 0.67 MAPT (0.50) KDM4EALDH1A1TDP1L3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2319890-A1 AZO COMPOUND, AZO PIGMENT, PIGMENT DISPERSION, COLOR COMPOSITION, INKJET RECORDING INK, COLOR COMPOSITION FOR COLOR FILTER, COLOR FILTER, AND METHOD FOR PREPARING COLOR COMPOSITION FOR COLOR FILTER FUJIFILM Corporation (JP) 2011-05-11 EP disclosed