Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658026 | 0.86 | NR4A2 (0.48) | PYGLMTNR1AMTNR1BHSD17B10NR4A2 | |
| SCHEMBL12658136 | 0.85 | F7 (0.45) | NR4A2NHERF1F7F3GABRP | |
| SCHEMBL12658119 | 0.81 | TSHR (0.47) | TSHRPYGLMTNR1AMTNR1BGFER | |
| SCHEMBL12658207 | 0.79 | NR4A2 (0.45) | PYGLMTNR1AMTNR1BHSD17B10NR4A2 | |
| SCHEMBL12658121 | 0.76 | IGF1R (0.37) | TSHRMTNR1AMTNR1BHSD17B10NR4A2 | |
| SCHEMBL12658115 | 0.73 | NR4A2 (0.45) | PYGLNR4A2F7F3 | |
| SCHEMBL12658015 | 0.72 | F7 (0.42) | NR4A2NHERF1F7F3 | |
| SCHEMBL12658126 | 0.71 | NR4A2 (0.44) | PYGLGFERHSD17B10NR4A2F7 | |
| SCHEMBL12658116 | 0.71 | NR4A2 (0.44) | PYGLNR4A2F7F3 | |
| Lynamicin A SCHEMBL12658027 | 0.70 | NR4A2 (0.61) | PYGLMTNR1AMTNR1BGFERHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711486-B1 | BIS-INDOLE PYRROLES USEFUL AS ANTIMICROBIAL AGENTS | NEREUS PHARMACEUTICALS INC (US) | 2011-05-11 | — | — | EP | disclosed |