Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27014465 | 0.84 | CARM1 (0.56) | CYP2D6KDM1AALDH1A1HRH3KCNH2 | |
| SCHEMBL4255830 | 0.82 | CHRM2 (0.56) | CYP2D6HRH3KCNH2MC4R | |
| SCHEMBL14198386 | 0.79 | BACE1 (0.50) | CYP2D6ALDH1A1 | |
| SCHEMBL8674414 | 0.79 | IDO1 (0.52) | CYP2D6CHRNB4CHRNA3 | |
| SCHEMBL677532 | 0.79 | IDO1 (0.52) | CYP2D6CHRNB4CHRNA3 | |
| SCHEMBL6988817 | 0.79 | HRH3 (0.49) | CYP2D6ALDH1A1HRH3KCNH2 | |
| SCHEMBL6332123 | 0.79 | — | — | |
| SCHEMBL13890145 | 0.78 | BACE1 (0.46) | CYP2D6CHRNB4CHRNA3 | |
| SCHEMBL11611214 | 0.77 | OPRD1 (0.42) | CYP2D6 | |
| SCHEMBL27455613 | 0.77 | L3MBTL1 (0.50) | ALDH1A1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947256-B2 | Biocompatible fluorescent imaging agents | VISEN MEDICAL, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947256-B2 | Biocompatible fluorescent imaging agents | VISEN MEDICAL, INC. (US) | 2011-05-24 | — | — | US | disclosed |