Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17863862 | 0.76 | HCRTR2 (0.41) | TSHRMAPK1HPGD | |
| SCHEMBL24630407 | 0.76 | COPS5 (0.43) | TSHRMAPK1NPC1LMNATP53 | |
| SCHEMBL20438338 | 0.60 | PPARG (0.38) | MAPTSMN1; SMN2 | |
| SCHEMBL19256890 | 0.58 | PTGS1 (0.35) | PTGS1 | |
| SCHEMBL14805664 | 0.58 | NPSR1 (0.39) | HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6284882 | 0.57 | NPSR1 (0.47) | TSHRNPC1LMNAMAPTHPGD | |
| SCHEMBL26564430 | 0.57 | CYP1A2 (0.34) | — | |
| SCHEMBL10175758 | 0.57 | COPS5 (0.39) | NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL10176188 | 0.57 | CYP1A2 (0.33) | NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL28217303 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467969-B1 | DNA MINOR GROOVE BINDING COMPOUNDS | UNIV STRATHCLYDE (GB) | 2011-05-18 | — | — | EP | disclosed |