SCHEMBL26564430

SCHEMBL26564430

CC(=O)c1nc(C)sc1C(C)C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
GAA P10253 1/20 0.34
CYP2C9 P11712 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1431563 0.84 COPS5 (0.39)
SCHEMBL15650922 0.82 MAPK1 (0.32)
SCHEMBL10176188 0.80 CYP1A2 (0.33) CYP1A2GAACYP2C9RXFP1
SCHEMBL24630405 0.79 RAB9A (0.36)
SCHEMBL17865363 0.78 HCRTR2 (0.38) CYP1A2GAACYP2C9RXFP1
SCHEMBL12292842 0.78 COPS5 (0.44) CYP1A2GAA
SCHEMBL28217303 0.78
SCHEMBL1431368 0.77 ALDH1A1 (0.47) CYP1A2GAA
SCHEMBL26997579 0.76
SCHEMBL23682669 0.76 GFER (0.36) CYP1A2GAACYP2C9RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257128-A2 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. (US) 2023-10-11 EP disclosed