Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COPS5 | Q92905 | 6/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292842 | 0.80 | COPS5 (0.44) | COPS5FBP1ALDH1A1CYP1A2GAA | |
| SCHEMBL353509 | 0.80 | COPS5 (0.58) | COPS5FBP1ALDH1A1CYP1A2HPGD | |
| SCHEMBL15652654 | 0.80 | COPS5 (0.44) | COPS5FBP1MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL17863862 | 0.79 | HCRTR2 (0.41) | GFERTSHRMAPK1ALDH1A1HPGD | |
| SCHEMBL1096595 | 0.76 | ALDH1A1 (0.51) | COPS5FBP1MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL12659982 | 0.76 | PTGS1 (0.32) | TSHRMAPK1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL13404132 | 0.76 | GFER (0.36) | GFERHPGDSMN1; SMN2NPC1LMNA | |
| SCHEMBL2082444 | 0.72 | ALDH1A1 (0.65) | COPS5FBP1ALDH1A1CYP1A2GAA | |
| SCHEMBL3197829 | 0.71 | KMT2A (0.43) | COPS5ALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL4121073 | 0.69 | FBP1 (0.52) | COPS5FBP1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150555-A2 | METHODS AND COMPOUNDS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2022-07-14 | — | — | WO | disclosed |