Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3791075 | 0.87 | ALDH1A1 (0.55) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL16956058 | 0.83 | ALDH1A1 (0.43) | ALDH1A1CYP3A4ACHEPTPN1MAPT | |
| SCHEMBL716226 | 0.79 | TPMT (0.48) | ALDH1A1CYP3A4ACHEMAPTGLA | |
| SCHEMBL12020820 | 0.79 | LMNA (0.48) | ALDH1A1CYP3A4ABCG2NPC1RAB9A | |
| SCHEMBL16956465 | 0.79 | CYP3A4 (0.36) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL309826 | 0.78 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL22991518 | 0.78 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL9419478 | 0.77 | TPMT (0.46) | ALDH1A1ACHEGLAHPGD | |
| SCHEMBL16953671 | 0.76 | CYP3A4 (0.38) | ALDH1A1CYP3A4ACHEPTPN1MAPT | |
| SCHEMBL19295887 | 0.76 | CYP3A4 (0.38) | ALDH1A1CYP3A4ACHEPTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125748-B1 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | ASTRAZENECA AB (SE) | 2011-05-25 | — | — | EP | disclosed |