Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12663239 | 0.87 | PDE4A (0.41) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22991518 | 0.85 | PDE4A (0.40) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL309826 | 0.85 | PDE4A (0.40) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL40552 | 0.79 | ALDH1A1 (0.61) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30854918 | 0.78 | NPC1 (0.63) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1790008 | 0.78 | NPC1 (0.63) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9731581 | 0.78 | ALDH1A1 (0.46) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2899096 | 0.75 | MAPT (0.63) | ALDH1A1MAPTKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL1792104 | 0.75 | MAPT (0.63) | ALDH1A1MAPTKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL863160 | 0.75 | MAPK1 (0.56) | ALDH1A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018662-A2 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |
| US-7687145-B2 | Compounds containing a thiol protected group bonded to a protecting group via a polarized bond, and structure comprising the compounds on its surface | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-30 | — | — | US | disclosed |
| US-20060273306-A1 | Compounds and methods for nanoscale patterning and structure formation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-12-07 | — | — | US | disclosed |
| US-4290943-A | Method of preparing polypeptides | MAX-PLANK-GESELLSCHAFT (DE) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060273306-A1 | Compounds and methods for nanoscale patterning and structure formation | AS3MT, MPST, TST | ALDH1A1 231/4885PDE4A 4416/4885PDE4B 4460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.