SCHEMBL12669255

SCHEMBL12669255

Cc1ccc(-c2cc(C)c(C)s2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.47
ESR2 Q92731 2/20 0.47
HSD17B1 P14061 6/20 0.39
HSD17B2 P37059 6/20 0.39
ACHE P22303 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 2/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
HSD17B10 Q99714 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
DAO P14920 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12777778 0.83 MAPT (0.45) ESR1ESR2HSD17B1HSD17B2ALDH1A1
SCHEMBL22946430 0.83 ESR1 (0.44) ESR1ESR2HSD17B1HSD17B2ACHE
SCHEMBL114000 0.82 HSD17B1 (0.47) ESR1ESR2HSD17B1HSD17B2ALDH1A1
SCHEMBL17066346 0.81 HSD17B1 (0.47) ESR1ESR2HSD17B1HSD17B2ACHE
SCHEMBL12361198 0.80 ESR1 (0.71) ESR1ESR2HSD17B1HSD17B2ACHE
SCHEMBL15591299 0.79 ESR1 (0.42) ESR1ESR2HSD17B1HSD17B2ALDH1A1
SCHEMBL13164261 0.79 APP (0.59) TDP1ALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL15591300 0.79 ESR1 (0.42) ESR1ESR2HSD17B1HSD17B2ALDH1A1
SCHEMBL14817171 0.78 TUBB4A (0.44) ESR1ESR2ACHETDP1ALDH1A1
SCHEMBL28848007 0.78 ESR1 (0.43) ESR1ESR2HSD17B1HSD17B2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 US disclosed
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 US disclosed
US-7943848-B2 Photoelectric conversion element, method of manufacturing the same and solar cell KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-05-17 US disclosed
US-7943848-B2 Photoelectric conversion element, method of manufacturing the same and solar cell KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-05-17 US disclosed
US-7794896-B2 Methods for making holographic data storage articles GENERAL ELECTRIC COMPANY (US) 2010-09-14 US disclosed
US-7794896-B2 Methods for making holographic data storage articles GENERAL ELECTRIC COMPANY (US) 2010-09-14 US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 US disclosed
US-20080115826-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD OF MANUFACTURING THE SAME AND SOLAR CELL KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-05-22 US disclosed
US-20080115826-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD OF MANUFACTURING THE SAME AND SOLAR CELL KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-05-22 US disclosed
US-20070097469-A1 Methods for making holographic data storage articles GENERAL ELECTRIC COMPANY (US) 2007-05-03 US disclosed
US-20070097469-A1 Methods for making holographic data storage articles GENERAL ELECTRIC COMPANY (US) 2007-05-03 US disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 US disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 US disclosed